Publications and patents

For citation counts and the most current list, see Google Scholar and ORCID.

Selected papers

A robust, real-time telemetry protocol for miniaturized neural implants using off-the-shelf hardware
A 2.4 GHz protocol on commercial hardware kept zero data loss down to −75 dBm, where Bluetooth Low Energy degraded below −55 dBm.
Bioelectronic Medicine, 2026
Control of spatiotemporal activation of organ-specific fibers in the swine vagus nerve by intermittent interferential current stimulation
Interferential currents from a multi-contact cuff steered activation between organ-specific fibers in the swine vagus nerve.
Nature Communications, 2025
Organ- and function-specific anatomical organization of vagal fibers supports fascicular vagus nerve stimulation
Vagal fibers are organized by organ and function inside the nerve, which supports stimulating individual fascicles.
Brain Stimulation, 2023
A fully implantable wireless bidirectional neuromodulation system for mice
A 2.2 cm³, 2.8 g recording and stimulation implant for mice, built from commercial parts and 3D-printed packaging and recharged wirelessly.
Biosensors and Bioelectronics, 2022

Bold: principal investigator · dotted underline: lab members

Journal articles29

A robust, real-time telemetry protocol for miniaturized neural implants using off-the-shelf hardware Elgohary M, Recine M, Wong J, Datta-Chaudhuri T Bioelectronic Medicine 12(1):8, 2026 Free full text Wireless implant Wireless telemetry
Dynamic, minimally invasive electrical brain stimulation improves speech perception Akkol S, Herrero JL, Espinal E, Markowitz N, Datta-Chaudhuri T, Mehta AD, Bickel S Hearing Research 476:109637, 2026
Control of spatiotemporal activation of organ-specific fibers in the swine vagus nerve by intermittent interferential current stimulation Rossetti N, Song W, Schnepel P, Jayaprakash N, Koutsouras DA, Fichman M, Wong J, Levy T, Elgohary M, Qanud K, Giannotti A, Barbe MF, Chen FL, Langereis G, Datta-Chaudhuri T, Mihajlović V, Zanos S Nature Communications 16(1):4419, 2025 Free full text Selective nerve stimulation
Vagus nerve stimulation: A targeted approach for reducing tissue-specific ischemic reperfusion injury Singh P, Chaudhary M, Kazmi JS, Kuschner CE, Volpe BT, Datta-Chaudhuri T, Becker LB Biomedicine & Pharmacotherapy 184:117898, 2025
Organ- and function-specific anatomical organization of vagal fibers supports fascicular vagus nerve stimulation Jayaprakash N, Song W, Toth V, Vardhan A, Levy T, Tomaio J, Qanud K, Mughrabi I, Chang YC, Rob M, Daytz A, Abbas A, Nassrallah Z, Volpe BT, Tracey KJ, Al-Abed Y, Datta-Chaudhuri T, Miller L, Barbe MF, Lee SC, Zanos TP, Zanos S Brain Stimulation 16(2):484-506, 2023 Free full text Selective nerve stimulation
Voltammetry in the spleen assesses real-time immunomodulatory norepinephrine release elicited by autonomic neurostimulation Mughrabi IT, Gerber M, Jayaprakash N, Palandira SP, Al-Abed Y, Datta-Chaudhuri T, Smith C, Pavlov VA, Zanos S Journal of Neuroinflammation 20(1):236, 2023 Free full text
The Fifth Bioelectronic Medicine Summit: today's tools, tomorrow's therapies Chang EH, Gabalski AH, Huerta TS, Datta-Chaudhuri T, Zanos TP, Zanos S, Grill WM, Tracey KJ, Al-Abed Y Bioelectronic Medicine 9(1):21, 2023 Free full text
A fully implantable wireless bidirectional neuromodulation system for mice Wright JP, Mughrabi IT, Wong J, Mathew J, Jayaprakash N, Crosfield C, Chang EH, Chavan SS, Tracey KJ, Pavlov VA, Al-Abed Y, Zanos TP, Zanos S, Datta-Chaudhuri T Biosensors and Bioelectronics 200:113886, 2022 Free full text Wireless implant Implant packaging
kHz-frequency electrical stimulation selectively activates small, unmyelinated vagus afferents Chang YC, Ahmed U, Jayaprakash N, Mughrabi I, Lin Q, Wu YC, Gerber M, Abbas A, Daytz A, Gabalski AH, Ashville J, Dokos S, Rieth L, Datta-Chaudhuri T, Tracey KJ, Guo T, Al-Abed Y, Zanos S Brain Stimulation 15(6):1389-1404, 2022 Free full text Selective nerve stimulation
High-frequency electrical stimulation attenuates neuronal release of inflammatory mediators and ameliorates neuropathic pain Yang H, Datta-Chaudhuri T, George SJ, Haider B, Wong J, Hepler TD, Andersson U, Brines M, Tracey KJ, Chavan SS Bioelectronic Medicine 8(1):16, 2022 Free full text
Effect of uniform capacitively coupled electric fields on matrix metabolism of osteoarthritic cartilage Noruzi K, Swami P, Frejo L, Wright J, Wong J, Grande D, Datta-Chaudhuri T Bioelectronic Medicine 8(1):14, 2022 Free full text
Vagus nerve stimulation: a potential therapeutic role in childhood nephrotic syndrome? Sethna CB, Merchant K, Zanos S, Deutschman CS, Datta-Chaudhuri T, Chavan S, Tracey KJ American Journal of Nephrology 53(4):290-296, 2022 Free full text
Transcutaneous auricular vagus nerve stimulation (taVNS) for the treatment of pediatric nephrotic syndrome: a pilot study Merchant K, Zanos S, Datta-Chaudhuri T, Deutschman CS, Sethna CB Bioelectronic Medicine 8(1):1, 2022 Free full text Wearable stimulation
Closed-loop neuromodulation will increase the utility of mouse models in Bioelectronic Medicine Datta-Chaudhuri T Bioelectronic Medicine 7(1):10, 2021 Free full text Wireless implant
The Fourth Bioelectronic Medicine Summit "Technology Targeting Molecular Mechanisms": current progress, challenges, and charting the future Datta-Chaudhuri T, Zanos T, Chang EH, Olofsson PS, Bickel S, Bouton C, et al., Tracey KJ Bioelectronic Medicine 7(1):7, 2021 Free full text
Development and characterization of a chronic implant mouse model for vagus nerve stimulation Mughrabi IT, Hickman J, Jayaprakash N, Thompson D, Ahmed U, Papadoyannis ES, et al., Datta-Chaudhuri T, et al., Zanos S eLife 10:e61270, 2021 Free full text
Transcutaneous auricular vagus nerve stimulation (tAVNS) delivered during upper limb interactive robotic training demonstrates novel antagonist control for reaching movements following stroke Chang JL, Coggins AN, Saul M, Paget-Blanc A, Straka M, Wright J, Datta-Chaudhuri T, Zanos S, Volpe BT Frontiers in Neuroscience 15:767302, 2021 Free full text Wearable stimulation
Implant- and anesthesia-related factors affecting cardiopulmonary threshold intensities for vagus nerve stimulation Ahmed U, Chang YC, Lopez MF, Wong J, Datta-Chaudhuri T, Rieth L, Al-Abed Y, Zanos S Journal of Neural Engineering 18(4):046075, 2021 Selective nerve stimulation
Electrochemical immunosensing of interleukin-6 in human cerebrospinal fluid and human serum as an early biomarker for traumatic brain injury Oh C, Park B, Li C, Maldarelli C, Schaefer JL, Datta-Chaudhuri T, Bohn PW ACS Measurement Science Au 1(2):65-73, 2021 Free full text
Transcutaneous auricular vagus nerve stimulation reduces pain and fatigue in patients with systemic lupus erythematosus: a randomised, double-blind, sham-controlled pilot trial Aranow C, Atish-Fregoso Y, Lesser M, Mackay M, Anderson E, Chavan S, Zanos TP, Datta-Chaudhuri T, Bouton C, Tracey KJ, Diamond B Annals of the Rheumatic Diseases 80(2):203-208, 2021 Wearable stimulation
Ultrasound powered piezoelectric neurostimulation devices: a commentary Sun T, Wright J, Datta-Chaudhuri T Bioelectronic Medicine 6:16, 2020 Free full text
Specific vagus nerve stimulation parameters alter serum cytokine levels in the absence of inflammation Tsaava T, Datta-Chaudhuri T, Addorisio ME, Masi EB, Silverman HA, Newman JE, Imperato GH, Bouton C, Tracey KJ, Chavan SS, Chang EH Bioelectronic Medicine 6:8, 2020 Free full text
Quantitative estimation of nerve fiber engagement by vagus nerve stimulation using physiological markers Chang YC, Cracchiolo M, Ahmed U, Mughrabi I, Gabalski A, Daytz A, Rieth L, Becker L, Datta-Chaudhuri T, Al-Abed Y, Zanos TP, Zanos S Brain Stimulation 13(6):1617-1630, 2020
Anodal block permits directional vagus nerve stimulation Ahmed U, Chang YC, Cracchiolo M, Lopez MF, Tomaio JN, Datta-Chaudhuri T, Zanos TP, Rieth L, Al-Abed Y, Zanos S Scientific Reports 10:9221, 2020 Free full text Selective nerve stimulation
Auricular neural stimulation as a new non-invasive treatment for opioid detoxification Qureshi IS, Datta-Chaudhuri T, Tracey KJ, Pavlov VA, Chen ACH Bioelectronic Medicine 6:7, 2020 Free full text
System-on-chip considerations for heterogeneous integration of CMOS and fluidic bio-interfaces Datta-Chaudhuri T, Smela E, Abshire PA IEEE Transactions on Biomedical Circuits and Systems 10(6):1129-1142, 2016
Low temperature co-fired ceramic packaging of CMOS capacitive sensor chip towards cell viability monitoring Halonen N, Kilpijärvi J, Sobocinski M, Datta-Chaudhuri T, Hassinen A, Prakash SB, Möller P, Abshire P, Kellokumpu S, Lloyd Spetz A Beilstein Journal of Nanotechnology 7(1):1871-1877, 2016
Olfaction on a chip Datta-Chaudhuri T, Araneda RC, Abshire P, Smela E Sensors and Actuators B: Chemical 235:74-78, 2016
Packaging commercial CMOS chips for lab on a chip integration Datta-Chaudhuri T, Abshire P, Smela E Lab on a Chip 14(10):1753-1766, 2014 Implant packaging

Conference papers13

A low-power implantable neurostimulator for small rodents with functional validation Wright J, Wong J, Chang YC, Ahmed U, Zanos S, Datta-Chaudhuri T IEEE Biomedical Circuits and Systems Conference (BioCAS), Nara, Japan, pp. 1-4, 2019 Wireless implant
Extraction of evoked compound nerve action potentials from vagus nerve recordings Chang YC, Ahmed U, Tomaio JN, Rieth L, Datta-Chaudhuri T, Zanos S 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Berlin, Germany, pp. 6278-6281, 2019
Characterization of an active micro-electrode array with spike detection and asynchronous readout Senevirathna B, Castro A, Datta-Chaudhuri T, Smela E, Abshire P IEEE 60th International Midwest Symposium on Circuits and Systems (MWSCAS), pp. 627-630, 2017
A scalable 20×20 fully asynchronous SPAD-based imaging sensor with AER readout Berkovich A, Datta-Chaudhuri T, Abshire P IEEE International Symposium on Circuits and Systems (ISCAS), pp. 1110-1113, 2015
Low temperature co-fired ceramic package for lab-on-CMOS applied in cell viability monitoring Halonen N, Kilpijärvi J, Sobocinski M, Datta-Chaudhuri T, Hassinen A, Prakash SB, Möller P, Abshire P, Smela E, Kellokumpu S, Lloyd Spetz A Procedia Engineering 120:1079-1082 (Eurosensors 2015), 2015
An active micro-electrode array with spike detection and asynchronous readout Datta-Chaudhuri T, Senevirathna B, Castro A, Smela E, Abshire P IEEE Biomedical Circuits and Systems Conference (BioCAS), pp. 588-591, 2014
System-on-chip considerations for CMOS fluidic and biointerface applications Datta-Chaudhuri T, Abshire P, Smela E IEEE International Symposium on Circuits and Systems (ISCAS), pp. 2009-2012, 2014
High resolution capacitance sensor array for real-time monitoring of cell viability Naviasky E, Datta-Chaudhuri T, Abshire P IEEE International Symposium on Circuits and Systems (ISCAS), pp. 634-637, 2014
Floating-gate capacitance sensor array for cell viability monitoring Datta T, Naviasky E, Abshire P IEEE Biomedical Circuits and Systems Conference (BioCAS), pp. 65-68, 2013
Confession session: Learning from others' mistakes Abshire P, Bermak A, Berner R, Cauwenberghs G, Chen S, Christen JB, Constandinou T, Culurciello E, Dandin M, Datta T, Delbruck T, et al. IEEE International Symposium on Circuits and Systems (ISCAS), pp. 1149-1162, 2011
Towards a legged chip Datta T, Abshire P, Turner JA IEEE International Symposium on Circuits and Systems (ISCAS), pp. 2501-2504, 2011
Mismatch compensation of a subthreshold CMOS current normalizer Sander D, Datta T, Abshire P IEEE International Symposium on Circuits and Systems (ISCAS), pp. 3409-3412, 2010
Mismatch compensation of CMOS current mirrors using floating-gate transistors Datta T, Abshire P IEEE International Symposium on Circuits and Systems (ISCAS), pp. 1823-1826, 2009

Letters and commentary1

A randomized, double-blind, sham-controlled, clinical trial of auricular vagus nerve stimulation for the treatment of active rheumatoid arthritis: comment on the article by Baker et al Aranow C, Datta-Chaudhuri T, Andersson U, Chavan S, Tracey KJ Arthritis & Rheumatology 77(9):1278-1279, 2025

Conference abstracts12

Spatiotemporal activation of vagus nerve fibers via intermittent interferential current stimulation Schnepel P, Rossetti N, Song W, Jayaprakash N, Koutsouras D, et al. Neuromodulation: Technology at the Neural Interface 29(1):S94, 2026
Development of polymer-based packaging for chronic wireless neuromodulation implants in mice Wong J, Mughrabi I, Hepler T, Elgohary M, Recine M, Datta-Chaudhuri T Bioelectronic Medicine 11(Suppl 1):P12 (6th Bioelectronic Medicine Summit), 2025 Wireless telemetry Implant packaging
Data loss mitigation techniques for wireless streaming of neural recording data from an implanted device Elgohary M, Recine M, Wong J, Datta-Chaudhuri T Bioelectronic Medicine 11(Suppl 1):P14 (6th Bioelectronic Medicine Summit), 2025 Wireless telemetry Implant packaging
Selective peripheral nerve stimulation: computational models to the rescue Rossetti N, Schnepel P, Mihajlović V, Song W, Datta-Chaudhuri T, Zanos S Bioelectronic Medicine 11(Suppl 1):P2 (6th Bioelectronic Medicine Summit), 2025 Wireless telemetry Implant packaging
Starting phase of kHz stimulation bursts impacts spatio-temporal pattern of fiber activation in porcine vagus nerve Rossetti N, Song W, Schnepel P, Jayaprakash N, Wong J, Elgohary M, et al. Brain Stimulation, 2025
High frequency electrical stimulation reduces neuronal HMGB1 release Yang H, Datta-Chaudhuri T, George SJ, Haider B, Wong J, Tracey KJ, et al. The Journal of Immunology 208(Suppl 1):52.13, 2022
Transcutaneous auricular vagus nerve stimulation (taVNS) for the treatment of pediatric nephrotic syndrome (NS) Sethna CB, Merchant K, Zanos S, Datta-Chaudhuri T, Singer P, et al. Journal of the American Society of Nephrology 32(10S):513, 2021
Engaging the cholinergic anti-inflammatory pathway by stimulating the vagus nerve reduces pain and fatigue in patients with SLE Aranow C, Lesser M, Mackay M, Anderson E, Zanos TP, Datta-Chaudhuri T, Bouton C, Tracey KJ, Diamond B Arthritis & Rheumatology 70 (suppl), ACR/ARHP Annual Meeting, 2018
Specific cytokine responses induced by selective vagus nerve stimulation Tsaava T, Datta-Chaudhuri T, Addorisio ME, Newman JE, Bouton C, Tracey KJ, Chavan SS Shock 49(6):126-127, 2018
Selective electrical stimulation of vagus nerve induces specific cytokine response Datta-Chaudhuri T, Tsaava T, Addorisio M, Bouton C, Tracey KJ, Chavan SS The Journal of Immunology 200(Suppl 1):43.11, 2018
Cell clinic; CMOS chip measuring capacitance as indication of cell adhesion applied in evaluating the cytotoxicity of nanomaterials Halonen N, Datta-Chaudhuri T, Hassinen A, Prakash SB, Möller P, Abshire P, Smela E, Kellokumpu S, Lloyd Spetz A Eurosensors 2014, Brescia, Italy, 2014
CMOS-based capacitance measurements applied in evaluating cell viability and cytotoxicity of nanomaterials Halonen N, Datta-Chaudhuri T, Hassinen A, Prakash SB, Möller P, Abshire P, Smela E, Kellokumpu S, Lloyd Spetz A E-MRS 2014 Spring Meeting, Lille, France, 2014

Thesis1

Integration of CMOS technology into lab-on-chip systems applied to the development of a bioelectronic nose Datta-Chaudhuri TB PhD dissertation, University of Maryland, College Park, 2015

Patents5

Systems and methods for closed-loop neuromodulation using multiple biological signals A fully implantable system that senses several biological signals, such as neural activity, ECG, pressure and motion, and adjusts nerve stimulation on its own. Datta-Chaudhuri TB The Feinstein Institutes for Medical Research
WO 2024/108110 EP 4601736 Research page
Apparatus for rapid detection of bacteria in fluids A disposable two-chamber cartridge and reader that removes the patient's own ATP, then detects bacterial ATP as light. Datta-Chaudhuri T, Danoff JR, Goldstein T, Asnis SE The Feinstein Institutes for Medical Research
US 2024/0351021 Research page
Implantable neuromodulation system for closed-loop stimulation and recording simultaneously at multiple brain sites An implantable system that records and stimulates at several brain sites at the same time, for closed-loop neuromodulation. Pannu SS, Shah KG, Chen S, Crosetti M, Datta-Chaudhuri TB, Felix SH, Ivanovskaya AN, Jones J, Lee KY, Patra S, Tolosa V, Tooker AC Lawrence Livermore National Security, LLC
US 11,801,381 B2
Air filtering surgical helmet A helmet worn under a surgical gown that delivers filtered air from a waist-worn unit to the wearer's face. Asnis S, Danoff J, Datta-Chaudhuri T, Goldstein T Northwell Health, Inc.
US 2022/0087356 Research page
Auricular stimulation device, system and methods of use An over-the-ear stimulator whose two offset electrodes rest on skin supplied by the auricular branch of the vagus nerve. Beamer P, Bouton CE, Datta-Chaudhuri TB, Martin A, Montalbano C, Montalbano G, Zanos TP The Feinstein Institutes for Medical Research
WO 2019/028000 EP 3661590 B1 CN 111356498 JP 2020-529240 CA 3071665 Research page